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Table 2 Descriptive statistic of total biomarker levels in human plasma

From: Biological variability dominates and influences analytical variance in HPLC-ECD studies of the human plasma metabolome

 

Metabolite measurements

Statistics

1st set of data (n = 14)*

2nd set of data (n = 10)**

 

Duplicates &Triplicates

Control

24-hours

48-hours

Mean ± SD

94.8± 52.5

85.1 ± 75.1

96.2 ± 83.4

97.6 ± 77.6

Mean median

82.3

60.1

67.7

71.8

Mean CV

57.1

82.7

83.8

76.4

Median CV

50.2

70.6

70.7

66.9

  1. * 66 metabolites
  2. ** 61 metabolites
  3. Mean ± SD: Each metabolite is scored relative to the standard pool, then each individual sample is assigned one value (the mean of its metabolites averaged across the duplicates and triplicates) and these means are then expressed as mean ± SD
  4. Mean Median: Average of the medians of the 66/61 variables across the population
  5. Mean CV: Average of the CVs of the 66/61 variables across the population
  6. Median CV: Median of the CVs of the 66/61 variables across the population
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BMC Clinical Pathology

ISSN: 1472-6890

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