Table 3 Sensitivity and specificity of HIV testing on sputum without CPC, comparing split and unsplit specimens
HIV serum ELISA (Standard) | ||||
|---|---|---|---|---|
HIV on sputum | Positive | Negative | Sensitivity (95% CI) | Specificity (95% CI) |
Split specimens | ||||
Day 4 | 93.3% (86.7–97.3%) | 73.7% (66.7–79.8%) | ||
Positive | 98 | 51 | ||
Negative | 7 | 135 | ||
Total | 105 | 186 | ||
Day 7 | 93.3% (86.6–97.3%) | 59.3% (50.8–67.4%) | ||
Positive | 97 | 59 | ||
Negative | 7 | 86 | ||
Total | 104 | 145 | ||
Unsplit specimens | ||||
Day 4 | 92.6% (75.7–99.1%) | 87.3% (75.5–94.7%) | ||
Positive | 25 | 7 | ||
Negative | 2 | 48 | ||
Total | 27 | 55 | ||
Day 7 | 91.3% (72.0–98.9%) | 72.9% (58.2–84.7%) | ||
Positive | 21 | 13 | ||
Negative | 2 | 35 | ||
Total | 23 | 48 | ||