An exfoliation and enrichment strategy results in improved transcriptional profiles when compared to matched formalin fixed samples

Table 2 Comparison of expression profiles between the three procurement groups

Comparison group	Number of gene probe sets with ≥ 2 fold change	Percentage of gene probe sets with ≥ 2 fold change
Group 1 vs. Group 2	13,544	25%
Group 1 vs. Group 3	699	1.9%
Group 2 vs. Group 3	10,344	19%

Comparison of results between sample procurement groups after amplification and hybridization onto Affymetrix HGU133 Plus 2.0 chips. Similarities in the expression profile were greatest between Groups 1 and 3, with significant differences apparent between Groups 1 and 2 and Groups 2 and 3.

ISSN: 1472-6890