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Table 4 Univariate analysis of the clinicopathological factors and tested markers for overall survival

From: The possible role of cell cycle regulators in multistep process of HPV-associated cervical carcinoma

Predictive variables

P value

Age (< 50; ≥ 50)

0.919

Tumor type

0.631

Tumor size (< 4 cm, ≥ 4 cm)

0.033

Tumor differentiation (well differentiated, poorly differentiated)

0.047

Lymph node status (positive, negative)

0.021

Stromal invasion (positive, negative)

0.664

Lymphovascular invasion (positive, negative)

0.831

Vaginal involvement (positive, negative)

0.532

FIGO stage (early, late)

0.011

Cyclin D1

0.011

Cyclin E

0.817

CDK4

0.532

p53

0.040

mdm-2

0.751

p21WAF

0.056

p16INK4A

0.855

p27KIP1

0.023

Rb

0.651

Ki-67

0.034