UPS | SPS | |||||
---|---|---|---|---|---|---|
pSS | Healthy controls | P-value | pSS | Healthy controls | P-value | |
Flow rate (ml/min/gland) | 0.00* (0.00–0.04) (n = 20) | 0.04 (0.00–0.13) (n = 20) | <0.001 | 0.10 (0.00–0.87) (n = 20) | 0.72 (0.17–1.57) (n = 20) | <0.001 |
pH | 5.5 (4.9–6.2) (n = 7) | 6.1 (5.4–6.6) (n = 14) | 0.008 | 6.8 (5.3–7.6) (n = 13) | 7.1 (6.8–8.0) (n = 19) | 0.020 |
PCO2 (KPa) | 2.5 (2.1–4.8) (n = 7) | 3.3 (0.5–7.9) (n = 14) | 0.455 | 3.5 (1.4–7.5) (n = 13) | 5.5 (0.3–10.0) (n = 19) | 0.021 |
Na+ (mM) | 7.0 (0.0–111.0) (n = 9) | 0.0 (0.0–8.5) (n = 19) | 0.002 | 15.5 (3.5–93.0) (n = 15) | 7.5 (0.0–65.0) (n = 20) | 0.034 |
K+ (mM) | 24.5 (4.5–52.5) (n = 9) | 29.0 (17.5–62.0) (n = 19) | 0.209 | 26.5 (12.0–53.0) (n = 15) | 23.0 (18.0–40.0) (n = 20) | 0.689 |
Total calcium (mM) | 1.0 (0.4–2.4) (n = 9) | 1.0 (0.6–4.1) (n = 16) | 0.887 | 1.1 (0.6–1.8) (n = 13) | 0.8 (0.4–1.4) (n = 20) | 0.008 |
Cl- (mM) | 22.5 (5.0–100.5) (n = 9) | 19.0 (12.0–43.0) (n = 19) | 0.588 | 27.0 (12.5–94.0) (n = 14) | 15.5 (9.0–59.0) (n = 20) | 0.037 |
Bicarbonate (mM) | 0.2 (0.0–0.8) (n = 8) | 0.8 (0.1–3.5) (n = 14) | 0.017 | 3.6 (0.1–26.8) (n = 12) | 11.3 (3.8–43.9) (n = 19) | 0.025 |
Total phosphate (mM) | 5.6 (2.3–15.0) (n = 7) | 9.3 (4.1–18.9) (n = 16) | 0.066 | 6.1 (2.1–8.2) (n = 11) | 5.2 (3.2–16.9) (n = 20) | 0.577 |
Total protein (mg/ml) | 1.11 (0.47–8.97) (n = 9) | 2.02 (0.64–5.34) (n = 18) | 0.316 | 1.33 (0.62–6.66) (n = 14) | 1.60 (0.84–4.19) (n = 20) | 0.589 |
Total protein output (mg/min) | 0 (0–0.18) (n = 9) | 0.07 (0–0.30) (n = 18) | <0.001 | 0.13 (0–1.38) (n = 14) | 1.30 (0.29–5.42) (n = 20) | <0.001 |
Amylase activity (μkat/l) | 7760 (3700–21200) (n = 7) | 5815 (1670–27140) (n = 18) | 0.193 | 5220 (560–17240) (n = 13) | 5520 (710–14710) (n = 20) | 0.624 |
β(mmol H+/l. pH unit) | 1.2 (0.1–2.9) (n = 7) | 4.0 (2.3–8.9) (n = 13) | <0.001 | 4.4 (0.5–6.7) (n = 10) | 5.2 (0.7–10.1) (n = 19) | 0.171 |
DSHAP | 1.4 (0.2–3.6) (n = 9) | 3.1 (2.5–10.4) (n = 16) | 0.001 | 7.3 (0.6–21.4) (n = 13) | 10.0 (4.5–22.0) (n = 19) | 0.372 |
Critical pH | 5.4 (5.1–6.2) (n = 7) | 5.3 (5.0–5.5) (n = 16) | 0.413 | 5.5 (5.2–6.2) (n = 11) | 5.7 (5.2–5.8) (n = 19) | 0.611 |