Table 3 Unstimulated (UWS) and stimulated (SWS) whole salivary flow rate and composition in the patients with primary Sjögren's syndrome (pSS, n = 20) and the healthy controls (n = 20). Results are given in median (range).
UWS | SWS | |||||
|---|---|---|---|---|---|---|
pSS | Healthy controls | P-value | pSS | Healthy controls | P-value | |
Flow rate (ml/min) | 0.02 (0.00–0.23) (n = 20) | 0.39 (0.06–1.10) (n = 20) | <0.001 | 0.14 (0.01–1.66) (n = 20) | 1.40 (0.54–2.82) (n = 20) | <0.001 |
Na+ (mM) | 12.0 (8.0–47.0) (n = 11) | 8.0 (4.5–17.0) (n = 20) | 0.008 | 16.0 (8.0–59.0) (n = 12) | 10.3 (5.5–30.0) (n = 20) | 0.020 |
K+ (mM) | 22.2 (5.1–48.0) (n = 11) | 21.9 (6.8–33.4) (n = 20) | 0.536 | 21.6 (15.2–34.6) (n = 12) | 22.0 (11.5–26.5) (n = 20) | 0.533 |
Total calcium (mM) | 2.0 (1.3–3.2) (n = 7) | 1.7 (0.5–2.8) (n = 19) | 0.285 | 1.3 (0.7–1.9) (n = 12) | 1.3 (0.8–2.5) (n = 20) | 0.558 |
Cl- (mM) | 25.8 (16.0–62.0) (n = 10) | 18.3 (5.2–26.0) (n = 19) | 0.003 | 22.6 (13.5–58.6) (n = 11) | 16.1 (10.5–28.6) (n = 20) | 0.037 |
Total phosphate (mM) | 6.0 (1.2–15.0) (n = 9) | 6.8 (2.4–11.7) (n = 19) | 0.961 | 4.4 (2.4–8.5) (n = 11) | 4.1 (1.6–11.5) (n = 20) | 0.606 |
Total protein (mg/ml) | 3.00 (1.52–8.84) (n = 8) | 3.29 (1.36–6.25) (n = 19) | 0.560 | 3.50 (0.421–8.93) (n = 12) | 3.04 (1.23–5.54) (n = 20) | 0.491 |
Total protein output (mg/min) | 0.210 (0.06–0.80) (n = 8) | 1.09 (0.50–2.38) (n = 19) | <0.001 | 0.95 (0.11–4.33) (n = 12) | 3.88 (2.35–8.06) (n = 20) | <0.001 |
Amylase activity (μkat/l) | 365 (0–4500) (n = 10) | 980 (0–8940) (n = 19) | 0.155 | 1490 (0–4080) (n = 12) | 2280 (0–5890) (n = 20) | 0.199 |