Figure 2
Total peritoneal leukocyte and neutrophil counts in WT and P/I null mice subjected to CLP or 2% glycogen-induced peritonitis. Wild-type (WT) and P/I null were subjected either to no treatment (Control), sham (Sham CLP), CLP, or 2% glycogen. The mice were then euthanized at 6, and 24 hours of treatment, peritoneal lavages were collected and analyzed for leukocyte and neutrophil contents. Data are expressed as mean ± SEM, representing the absolute number of cells X 106 per each lavage. Significant differences existed between sham, CLP and 2% glycogen as compared to their respective control group (* p < 0.05), and as P/I null mice compared to respective wild-type at the same time period and treatment (# p ≤ 0.05). Data from six independent experiments with total sample size of 4 mice per each control and 2% glycogen group, 6 to 8 mice per each sham and 8 to 11 mice per each CLP treatment group.