Skip to main content
Figure 8 | BMC Clinical Pathology

Figure 8

From: Optimization of biotinyl-tyramide-based in situ hybridization for sensitive background-free applications on formalin-fixed, paraffin-embedded tissue specimens

Figure 8

CIN II Lesion Hybridized with HPV Probe. A. A CIN II lesion hybridized with DAKO wide-spectrum probe and incubated with AEC for 10 minutes. Diffuse and punctate signals are evident (arrows). B. Tissue from the same lesion incubated with DAB for 3 minutes. Diffuse and puncate signals are evident but there are also numerous punctate-like signals not associated with cell nuclei that compromise interpretation. Scale Bar: 10μm

Back to article page