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Table 1 Patient characteristics and their variables as predictors for disease-specific survival in 335 NSCLC patients (univariate analyses; log-rank test)

From: High tumor cell expression of microRNA-21 in node positive non-small cell lung cancer predicts a favorable clinical outcome

Characteristics Patients Median survival month 5-year survival % P
n (91)
Age      
  ≤65years 156 (47) 98 55 0.42
  > 65 years 179 (53) NR 60
Sex      
  Female 82 (24) 190 64 0.22
  Male 253 (76) 98 56
Smoking      
  Never 15 (5) 19 43 0.26
  Current 215 (64) NR 60
  Former 105 (31) 84 55
Performance status      
  PS 0 197 (59) NR 63 0.016
  PS 1 120 (36) 64 52
 PS 2 18 (5) 25 33
Weight loss      
  <10% 303 (90) 190 58 0.76
  >10% 32 (10) 98 57
Histology      
  SCC 191 (57) NR 66 0.028
  Adenocarcinoma 113 (34) 54 46
  LCC 31 (9) 98 56
Differentiation      
  Poor 138 (41) 47 47 <0.001
  Moderate 144 (43) 190 65
  Well 53 (16) NR 68
Surgical procedure      
  Lobectomy + Wedge* 243 (73) 190 62 0.007
  Pitunionectomy 92 (27) 37 47
Pathological stage      
  I 157 (47) NR 61 <0.001
  II 136 (40) 62 51
  IIIa 42 (13) 17 23
Tumor status      
  1 85 (25) 190 75 <0.001
  2 188 (56) 84 57
  3 62 (19) 25 36
Nodal status      
  0 232 (69) NR 67 <0.001
  1 76 (23) 35 43
  2 27 (8) 18 18
Surgical margins      
  Free 3)7 (92) 190 59 0.37
  Not free 28 (8) 47 48
Vascular infiltration      
  No 284 (85) 190 62 0.001
  Yes 51 (15) 27 33
  1. *Wedge, n= 10.
  2. Abbreviations: NR not reached, PS performance status, SCC squanos cell carcinoma, LCC large-cell carcinoma.
  3. Statistically significant results in bold font.