Table 1 Patient characteristics and their variables as predictors for disease-specific survival in 335 NSCLC patients (univariate analyses; log-rank test)
Characteristics | Patients | Median survival month | 5-year survival % | P | |
|---|---|---|---|---|---|
n | (91) | ||||
Age | |||||
≤65years | 156 | (47) | 98 | 55 | 0.42 |
> 65 years | 179 | (53) | NR | 60 | |
Sex | |||||
Female | 82 | (24) | 190 | 64 | 0.22 |
Male | 253 | (76) | 98 | 56 | |
Smoking | |||||
Never | 15 | (5) | 19 | 43 | 0.26 |
Current | 215 | (64) | NR | 60 | |
Former | 105 | (31) | 84 | 55 | |
Performance status | |||||
PS 0 | 197 | (59) | NR | 63 | 0.016 |
PS 1 | 120 | (36) | 64 | 52 | |
PS 2 | 18 | (5) | 25 | 33 | |
Weight loss | |||||
<10% | 303 | (90) | 190 | 58 | 0.76 |
>10% | 32 | (10) | 98 | 57 | |
Histology | |||||
SCC | 191 | (57) | NR | 66 | 0.028 |
Adenocarcinoma | 113 | (34) | 54 | 46 | |
LCC | 31 | (9) | 98 | 56 | |
Differentiation | |||||
Poor | 138 | (41) | 47 | 47 | <0.001 |
Moderate | 144 | (43) | 190 | 65 | |
Well | 53 | (16) | NR | 68 | |
Surgical procedure | |||||
Lobectomy + Wedge* | 243 | (73) | 190 | 62 | 0.007 |
Pitunionectomy | 92 | (27) | 37 | 47 | |
Pathological stage | |||||
I | 157 | (47) | NR | 61 | <0.001 |
II | 136 | (40) | 62 | 51 | |
IIIa | 42 | (13) | 17 | 23 | |
Tumor status | |||||
1 | 85 | (25) | 190 | 75 | <0.001 |
2 | 188 | (56) | 84 | 57 | |
3 | 62 | (19) | 25 | 36 | |
Nodal status | |||||
0 | 232 | (69) | NR | 67 | <0.001 |
1 | 76 | (23) | 35 | 43 | |
2 | 27 | (8) | 18 | 18 | |
Surgical margins | |||||
Free | 3)7 | (92) | 190 | 59 | 0.37 |
Not free | 28 | (8) | 47 | 48 | |
Vascular infiltration | |||||
No | 284 | (85) | 190 | 62 | 0.001 |
Yes | 51 | (15) | 27 | 33 | |