Table 1 Prognostic clinicopathological variables as predictors for disease-specific survival, metastasis and local recurrence in patients with resected Extremitiy & Trunk and Visceral & Retroperitoneal soft-tissue sarcomas (univariate analyses, log rank test, n = 115 and 66 respectively)

Age

≤ 20 years

12

42

0.431

42

0.129

73

0.690

1

0

<0.001

100

0.112

100

0.786

21-60 years

48

61

63

69

36

71

67

71

> 60 years

55

55

69

64

29

43

44

62

Gender

Male

57

56

0.298

66

0.368

66

0.759

15

79

0.039

86

0.022

66

0.799

Female

58

54

61

67

51

51

48

68

Patient nationality

Norwegian

67

65

0.004

74

0.008

71

0.249

54

62

0.051

59

0.122

66

0.892

Russian

48

42

48

57

12

36

46

59

Histological entity

Pleomorphic sarcoma

48

42

0.004

61

0.001

56

0.664

6

50

0.917

67

0.264

40

0.274

Leiomyosarcoma

9

100

78

78

39

55

46

77

Liposarcoma

18

83

94

89

13

62

81

54

Fibrosarcoma

12

57

67

55

0

Angiosarcoma

5

40

20

67

2

50

50

50

Rhabdomyosarcoma

5

60

60

60

1

100

100

MPNST

5

53

60

60

4

67

100

100

Synovial sarcoma

10

13

30

64

1

100

0

0

Sarcoma NOS

3

100

67

67

0

Tumor size

< 5 cm

38

70

0.048

81

0.053

74

0.085

11

82

0.107

73

0.259

89

0.006

5-10 cm

45

48

53

61

24

62

62

70

> 10 cm

30

49

58

62

31

45

45

49

Missing

2

Malignancy grade

1

29

89

<0.001

89

0.001

85

0.054

23

78

0.005

77

0.051

86

0.046

2

41

56

65

60

29

46

42

58

3

45

35

43

57

14

46

47

49

Vascular invasion

Absent

64

70

<0.001

85

<0.001

79

<0.001

43

59

0.656

60

0.847

66

0.675

Present

50

35

33

43

20

51

54

78

Missing

1

3

Tumor depth

Superficial

12

91

0.010

100

0.012

91

0.041

32

Deep

103

51

59

63

34

Resection margins

Wide

61

66

0.004

72

0.045

82

<0.001

50

65

0.021

59

0.654

90

<0.001

Non-wide

54

44

54

46

16

50

53

44