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Table 2 The relationship between adiponectin and various markers of insulin resistance before and after adjusting for BMI and duration of therapy, separately and together

From: High Molecular Weight (HMW): total adiponectin ratio is low in hiv-infected women receiving protease inhibitors

Relationship between adiponectin and markers of insulin resistance

  

Univariable

 

Multivariable

  
    

Adjusted for BMI

Adjusted for duration of therapy

Adjusted for BMI and duration of therapy

 

b

95% CI

p-value

b

95% CI

p-value

b

95% CI

p-value

b

95% CI

p-value

Total Adiponectin

            

Waist

-0.27

(-0.3895,-0.1420)

0.0001**

-0.28

(-0.5153,-0.0517)

0.019*

-0.29

(-0.4582,-0.1161)

0.002*

-0.35

(-0.6479,-0.0492)

0.028*

Fasted Insulin

-0.28

(-0.4683,-0.0906)

0.005*

-0.21

(-0.3945,-0.0164)

0.037*

-0.28

(-0.5408,-0.0266)

0.036*

-0.24

(-0.4935,0.0099)

0.067

HOMA-IR

-1.11

(-1.8677,-0.3428)

0.006*

-0.81

(-1.5741,-0.0551)

0.040*

-1.21

(-2.3196,-0.1036)

0.038*

-1.07

(-2.1435,0.0051)

0.058

QUICKI

14.20

(1.2607,27.1444)

0.035*

8.24

(-4.8207,21.3036)

0.221

15.25

(-0.2780,30.7806)

0.061

11.29

(-4.4271,26.9992)

0.167

HMW Adiponectin

            

Waist

-0.17

(-0.2484,-0.0923)

0.0001**

-0.19

(-0.3350,-0.0429)

0.014*

-0.16

(-0.2637,-0.0627)

0.003*

-0.19

(-0.3674,-0.0109)

0.044*

Fasted Insulin

-0.17

(-0.2941,-0.0547)

0.006*

-0.13

(-0.2475,-0.0078)

0.041*

-0.17

(-0.3204,-0.0169)

0.035*

-0.14

(-0.2918,0.0048)

0.065

HOMA-IR

-0.69

(-1.1753,-0.2091)

0.007*

-0.51

(-0.9903,-0.0273)

0.042*

-0.72

(-1.3745,-0.0666)

0.037*

-0.64

(-1.2681,-0.0022)

0.056

QUICKI

9.38

(1.2388,17.5231)

0.027*

5.67

(-2.5563,13.9009)

0.182

9.97

(0.9112,19.0352)

0.037*

7.66

(-1.5098,16.8289)

0.110

HMW: TA

            

Waist

-0.007

(-0.0102,-0.0042)

0.000**

-0.011

(-0.0165,-0.0054)

0.0003**

-0.16

(-0.2637,-0.0627)

0.003*

-0.007

(-0.0130,-0.0016)

0.016*

Fasted Insulin

-0.008

(-0.0123,-0.0030)

0.002*

-0.006

(-0.0109,-0.0014)

0.013*

-0.007

(-0.0119,-0.0025)

0.005*

-0.006

(-0.0111,-0.0018)

0.009*

HOMA-IR

-0.03

(-0.0497,-0.0123)

0.002*

-0.03

(-0.0442,-0.0063)

0.011*

-0.03

(-0.0509,-0.0103)

0.005*

-0.03

(-0.0479,-0.0084)

0.008*

QUICKI

0.42

(0.1036,0.7331)

0.011*

0.30

(-0.0230,0.6253)

0.073

0.44

(0.1586,0.7148)

0.004*

0.38

(0.0911,0.6598)

0.014*

  1. HMW, high molecular weight; b, coefficient; CI, confidence interval. *p < 0.05; **p < 0.001.