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Table 2 Cox regression analysis summarizing significant independent prognostic factors in patients with squamous cell carcinoma and normal performance status (ECOG = 0), n = 107

From: Prognostic value of the MicroRNA regulators Dicer and Drosha in non-small-cell lung cancer: co-expression of Drosha and miR-126 predicts poor survival

Factor

HR

95% CI

P

Tumor status

  

0.021*

 1

1.00

  

 2

2.52

0.82 – 7.79

0.108

 3

5.11

1.54 – 16.89

0.008

Nodal status

  

0.001*

 0

1.00

  

 1

2.11

1.21 – 2.89

0.045

 2

20.06

3.70 – >99

0.001

Differentiation

  

0.587*

 Poor

1.00

  

 Moderate

0.64

0.26 – 1.56

0.328

 Well

0.72

0.23 – 2.26

0.578

Vascular infiltration

   

 No

1.00

  

 Yes

3.10

1.29 – 7.42

0.011

Dicer

   

 Low

1.00

  

 High

0.30

0.10 – 0.90

0.031

  1. *Overall significance as a prognostic factor.
  2. HR: Hazard ratio; CI: confidence interval.