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Figure 4 | BMC Clinical Pathology

Figure 4

From: Estrogen receptor alpha and androgen receptor are commonly expressed in well-differentiated liposarcoma

Figure 4

Intratumor heterogeneity in degree of differentiation contributes to heterogeneity in hormone receptor expression. A) Frequencies of hormone receptor expression among WDLS specimens obtained from tumors classified as DDLS. B) Tumors for which 2 specimens were obtained from different regions at the same time point were evaluated for concordance in hormone receptor expression using a threshold of 10% for positivity. Scatterplots show% positive nuclei for ER and AR in tumors for which one DDLS specimen and one WDLS specimen were available. C) Representative liposarcoma specimens showing regions of receptor-positivity and -negativity. D) Hormone receptor status for patients with WDLS/DDLS as determined using any LS specimen obtained from any surgery.

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BMC Clinical Pathology

ISSN: 1472-6890

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