Table 1 Molecularly characterized grade IV glioblastoma GBM tumors
Patient no. | IDH 1/2 | EGFR amplification | MGMT promoter |
|---|---|---|---|
1 | No mutations detected | Amplified | Not assessed |
2 | No mutations detected | Amplified | Un-methylated |
3 | No mutations detected | Amplified | Un-methylated |
4 | IDH1 exon 4 R132H mutation detected; no mutation in exon 4 of IDH2 | Amplified | Methylated |
5 | No mutations detected | Not amplified | Methylated |
6 | No mutations detected | Amplified | Methylated |
7 | No mutations detected | Not amplified | Un-methylated |