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Table 5 Immunhistochemistry comparison between Dual-Modular Neck and the Metal-on-Metal (MoM) total hip arthroplasty (THA) groups

From: Implant based differences in adverse local tissue reaction in failed total hip arthroplasties: a morphological and immunohistochemical study

Perivascular region

Interstitial region

 

Dual-Modular Neck THA (N = 15)

MoM THA (N = 12)

P value

Dual-Modular Neck THA (N = 15)

MoM THA (N = 12)

P value

CD20:CD3

  

*0.032

  

0.35

1:2

46.1%

0%

 

85.7%

66.7%

 

1:1

30.8%

25.0%

 

14.3%

25.0%

 

2:1

23.1%

75.0%

 

0%

8.3%

 

CD4:CD8

      

1:2

15.4%

14.3%

0.964

50.0%

16.7%

0.189

1:1

23.1%

28.6%

 

35.7%

66.7%

 

2:1

61.5%

57.1%

 

14.3%

16.7%

 

GATA3:Tbet

      

1:2

0%

0%

1.00

0%

0%

0.42

1:1

0%

0%

 

38.5%

22.2%

 

2:1

100%

100%

 

61.5%

77.8%

 
  1. All values listed as percentage of cases representing qualitative grade for each antibody. *statistically significant at p < 0.05 for Dual-Modular Neck versus MoM THA.
  2. Immunohistochemistry Characteristics of Synovial Tissue from Dual-Modular Neck and MoM THA Groups.