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Figure 2 | BMC Clinical Pathology

Figure 2

From: Implant based differences in adverse local tissue reaction in failed total hip arthroplasties: a morphological and immunohistochemical study

Figure 2

Histopathologic images from MoM THA group A) Periprosthetic neo-synovium with polypoid hypertrophy (whole mount). B) Superficial macrophagic infiltrate with exfoliation of necrotic elements without significant lymphocytic response (x100). C) Corrosion product-laden macrophages with exfoliation of viable and necrotic elements (x200). D) Synovial papilla with particle-laden macrophages at different stages of degeneration with foamy elements (x200). E) Late stage of reaction with thick layer of necrosis and deep seated inflammatory infiltrate (whole mount). F) Band-like mixed inflammatory infiltrate and deep perivascular lymphocytic infiltrate (x100). G) Evidence of germinal center formation (lower left corner) and tall endothelial cell venule (x400) with positive staining for CD123 (inset x400). H) Bone marrow with benign reactive lymphocytic aggregate mixed with particle-laden macrophages (x200).

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