P53 nuclear stabilization is associated with FHIT loss and younger age of onset in squamous cell carcinoma of oral tongue

Table 4 Correlation of FHIT LOH with p53 stabilization and tobacco use

P53 status	n	Tobacco users (50)		Tobacco never users (23)
		*FHIT* LOH+	*FHIT* LOH-	*FHIT* LOH+	*FHIT* LOH-
NS+	45	09	24	08	4
NS-	28	04	13	01	10
				p value = 0.0094

FHIT LOH+, FHIT LOH present; FHIT LOH-, FHIT LOH absent; NS+, p53 nuclear stabilization; NS-, absence of p53 nuclear stabilization; n, Number of samples; LOH, loss of heterozygosity.
p value corresponds to Fisher’s exact test.

ISSN: 1472-6890