Compound | Plasma/serum concentrations | Cross-reactivity in Roche assay | Likelihood of clinically significant cross-reactivity |
---|---|---|---|
Estradiol (endogenous compound) | • 0.01 – 0.04 ng/mL (males) [37] | 100% | High (assay target) |
• 0.013 – 0.50 ng/mL (premenopausal females) [37] | |||
• Up to 4.3 ng/mL (pregnancy) [37] | |||
Estrone | • Up to 0.06 ng/mL (males) [24] | 0.54% | Low |
• Up to 0.2 ng/mL (females) [24] | |||
Ethinyl estradiol | 0.23% | Low | |
Estriol | • Up to 18 ng/mL in pregnancy [42] | 0.09% | Possible contribution in pregnancy |
 | • Up to 2.4 ng/mL in non-pregnant females [43] |  |  |