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Table 3 Evolution of biological parameters and BMD in patient 2

From: Giant osteoclasts in patients under bisphosphonates

  -36 months -24 months -12 months Bone biopsy +3 months
CTX (250–4500 pmol/L) 13700 ND 4760 3650 6545
Intact PTH (10–65 pg/mL) 127 ND 111 51 59
25-(OH) D (20–90 nmol/L) 22 40 60 62 82
Bone Alkaline      
Phosphatase (11.6-30.6 U/L) 21 7 9 10 11
BMD (T-score)      
Lumbar -2.6 ND ND -3.3 ND
Femoral neck -3.1    -3.5  
  1. CTX: Carboxy-terminal collagen crosslinks; PTH: Parathyroid hormone; BMD: Bone mineral density, ND: not determined.