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Table 1 Evolution of biological parameters and BMD in patient 1

From: Giant osteoclasts in patients under bisphosphonates

 

-48 months

-24 months

-12 months

Bone biopsy

-6 months

-12 months

-36 months

Deoxypyridinoline (8.2-20.2 nmol/mmol creat)

16.8

4.3

8.3

8.9

24.1

14.6

6.9

Intact PTH (10-65 pg/mL)

27.4

ND

ND

37.3

ND

52.1

65.1

25-(OH) D (20-90 nmol/L)

45

ND

ND

57

ND

79

94

Alkaline phosphatase (30-125 U/L)

72

ND

ND

53

97

93

47

BMD (T-score)

       

Lumbar

-1.2

-1.3

ND

-1.1

-1.2

-0.8

ND

Femoral neck

-0.6

-0.7

 

-0.4

-0.2

-0.6

 
  1. PTH: Parathyroid hormone; BMD: Bone mineral density; ND: not determined.