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Table 1 Evolution of biological parameters and BMD in patient 1

From: Giant osteoclasts in patients under bisphosphonates

  -48 months -24 months -12 months Bone biopsy -6 months -12 months -36 months
Deoxypyridinoline (8.2-20.2 nmol/mmol creat) 16.8 4.3 8.3 8.9 24.1 14.6 6.9
Intact PTH (10-65 pg/mL) 27.4 ND ND 37.3 ND 52.1 65.1
25-(OH) D (20-90 nmol/L) 45 ND ND 57 ND 79 94
Alkaline phosphatase (30-125 U/L) 72 ND ND 53 97 93 47
BMD (T-score)        
Lumbar -1.2 -1.3 ND -1.1 -1.2 -0.8 ND
Femoral neck -0.6 -0.7   -0.4 -0.2 -0.6  
  1. PTH: Parathyroid hormone; BMD: Bone mineral density; ND: not determined.