Table 4 Univariate and multivariate analyses to predict specimen Gleason score ≥ 7

FAS expression in biopsy cores (Low vs. High)

< 0.0001

10.62

3.71-35.65

0.0012

34.15

3.42 - 1145.4

Clinical T stage (cT1 vs. cT2 ≤)

0.0293

3.66

1.13-16.49

0.4890

2.29

0.23 - 32.36

Needle biopsy Gleason score ( ≤ 6 vs. 7≤)

< 0.0001

72.45

17.84-499.7

< 0.0001

228.17

25.37 - 8358.31

PSA (ng/ml)

0.0174

1.09

1.01-1.19

0.0202

1.22

1.03 -1.57

Positive core rate (%) (≤ 40% vs. 40% <)

0.007

5.76

1.53-37.7

0.9106

1.14

0.10 - 10.95

Total biopsy cores (≤ 8 vs. 8 <)

0.4131

1.48

0.58-3.84

0.9423

1.08

0.14 - 8.42