Table 7 Univariate Cox regression analysis for all examined markers in terms of DFS and OS
DFS | ||||
|---|---|---|---|---|
HR | 95% CI | Wald’s p | ||
Parameter | Category vs. the reference | |||
BRCA1 mutation status | Mutated | 1.68 | (0.59-4.80) | 0.33 |
BRCA1 protein expression | Positive | 0.99 | (0.65-1.51) | 0.95 |
alphaB-crystallin | 0.79 | |||
Weakly positive | 1.02 | (0.72-1.45) | 0.91 | |
Strongly positive | 1.14 | (0.77-1.69) | 0.50 | |
alphaB-crystallin (strongly positive vs. weakly positive/negative) | Strongly positive | 1.14 | (0.77-1.68) | 0.51 |
p53 protein expression | Positive | 1.21 | (0.97-1.50) | 0.088 |
OS | ||||
HR | 95% CI | Wald’s p | ||
Parameter | Category vs. the reference | |||
BRCA1 mutation status | Mutated | 1.75 | (0.52-5.86) | 0.36 |
BRCA1 protein expression | Positive | 0.95 | (0.57-1.58) | 0.86 |
alphaB-crystallin | 0.14 | |||
Weakly positive | 0.98 | (0.65-1.49) | 0.94 | |
Strongly positive | 1.52 | (1.00-2.31) | 0.050 | |
alphaB-crystallin (strongly positive vs. weakly positive/negative) | Strongly positive | 1.52 | (1.01-2.30) | 0.046 |
p53 protein expression | Positive | 1.24 | (0.98-1.65) | 0.066 |