Figure 2

Reflection of tissue heterogeneity by Spiral Array. A) Ki-67 immunohistochemical staining of lung adenocarcinoma shows variable amounts of positive cells within the slide. Red line indicates the area of coverage inside the Spiral Array (bar = 5 mm). Both high expression area of Ki-67 (B) and low expression area of Ki-67 (C) are included inside the same reel of Spiral Array.