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Table 1 Examples of exclusion criteria that either lead to, or potentially could have caused death, based upon macroscopic and histological findings in 1,190 infant autopsy cases based upon differing organs

From: Reference ranges for organ weights of infants at autopsy: results of >1,000 consecutive cases from a single centre

Organ

Exclusion criteria on macroscopic findings

Exclusion criteria on histological findings

Cases included

Heart

Myocardial Infarction, Ruptured ventricular aneurysm, Transplanted Heart, Cardiomyopathy

Myocarditis; rejection; extensive myocardial infarction

868

Lungs

Empyema, Laryngeal Stenosis/Atresia, Abscess, pulmonary hypoplasia as provided in the post-mortem report

TB, PCP Pneumonitis, Chronic Lung Disease, Asthma

764

Liver

Moderate to severe necrosis/infarction, tumour, haemorrhage

Acute or chronic hepatitis with necrosis, liver abscesses, neoplasia

1051

Spleen

Splenic laceration, haematoma

Abscess, malignancy or acute splenic sequestration

1101

Kidneys

Neoplasia, cystic dysplasia.

Neoplasia, dysplasia, cystic disease, glomerulonephritis or severe acute rejection.

1040

Pancreas

Neoplasia, haemorrhage, necrosis

Neoplasia, necrosis

1025

Thymus

Abscess or thymus encased in pus

Lymphoma, or Langerhans Cell Histiocytosis

1023

Adrenals

Abscesses, hypoplasia, necrosis or haemorrhage

Neoplasia, haemorrhage with necrosis

1039