Clinico-pathological features of tuberculosis due to Mycobacterium tuberculosis Uganda genotype in patients with tuberculous lymphadenitis: a cross sectional study

Table 2 Clinical and immunopathological parameters of patients infected with Uganda genotype and those infected by non-Uganda genotypes of M. tuberculosis

Patient characteristics	Uganda/Non-Uganda n (%)	Crude		Adjusted*
Patient characteristics	Uganda/Non-Uganda n (%)	OR (95% CI)	P-value	OR (95% CI)	P-value
Clinical presentations
Fever less than 6 months	39 (70%)/44 (69%)	1.0 (0.5-2.3)	0.916	1.1 (0.5-2.5)	0.870
Night sweats	43 (77%)/55 (86%)	0.5 (0.2-1.4)	0.200	0.5 (0.2-1.4)	0.213
Cough	27 (48%)/30 (46%)	1.1 (0.5-2.2)	0.821	1.4 (0.7-3.1)	0.435
Radiological Presentations
Abnormal Chest X-ray	20 (43%)/27 (47%)	0.8 (0.4-1.8)	0.624	0.8 (0.4-1.9)	0.644
Abdominal lymphadenopathy	21 (38%)/39 (60%)	0.4 (0.2-0.8)	0.014	0.5 (0.2-1.0)	0.046
Lymph node Pathology
Single site lymphadenitis	34 (62%)/32 (50%)	1.6 (0.8-3.4)	0.197	1.4 (0.6-2.9)	0.435
Generalized lymphadenopathy	5 (9%)/11 (17%)	0.5 (0.2-1.5)	0.204	0.7 (0.2-2.1)	0.474
Lymph node ≥ 4 cm	15 (28%)/28 (45%)	0.5 (0.2-1.0)	0.055	0.6 (0.3-1.3)	0.157
Necrosis	52 (93%)/61 (94%)	0.9 (0.2-3.6)	0.827	0.8 (0.2-3.4)	0.741
Giant cells	28 (50%)/25 (38%)	1.6 (0.8-3.3)	0.203	1.3 (0.6-2.8)	0.569
Macrophages	53 (95%)/58 (89%)	2.1 (0.5-8.7)	0.290	1.5 (0.4-6.9)	0.577
Granulomas	47 (84%)/46 (71%)	2.2 (0.9-5.3)	0.091	1.9 (0.8-4.8)	0.196
Ziehl Neelsen positive smear	29 (52%)/42 (65%)	0.6 (0.3-1.2)	0.152	0.7 (0.3-1.5)	0.348

Adjusted* = Adjusted for Age, Sex and HIV status; OR = Odds ratio, Cl = Confidence Interval.
Logistic regression.

ISSN: 1472-6890