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Table 3 Association of p53 expression with clinicopathological parameters

From: Colorectal cancer in patients seen at the teaching hospitals of Guadeloupe and Martinique: discrepancies, similarities in clinicopathological features, and p53 status

Parameters

GlpeTH and MqueTH

Ā 

p53positve

p53negative

p value

Ā 

nā€‰=ā€‰121 (%)

nā€‰=ā€‰72 (%)

Ā 

Mean age

67.2

70.8

0.10(a)

Range

24 - 99

31 - 93

Ā 

Age

Ā Ā 

0.68(b)

ā‰¤ 50Ā years

20 (16.5)

10 (13.9)

Ā 

> 50Ā years

101 (83.5)

62 (86.1)

Ā 

Sex

Ā Ā 

1.0(b)

Male

60 (49.6)

35 (48.6)

Ā 

Female

61 (50.4)

37 (51.4)

Ā 

Histologycal type

Ā Ā 

0.38(c)

ADK

110 (90.9)

61 (84.7)

Ā 

Mucinous ADK

8 (6.6)

7 (9.7)

Ā 

Other

3 (2.5)

4 (5.6)

Ā 

Tumour site

Ā Ā 

0.072(c)

Colon*

55 (45.5)

45 (62.5)

Ā 

sigmoid

46 (38.0)

19 (26.4)

Ā 

Rectum

20 (16.5)

8 (11.1)

Ā 

Tumour site

Ā Ā 

0.026(b)

Colon* yes

55 (45.5)

45 (62.5)

Ā 

Colon no

66 (54.5)

27 (37.5)

Ā 

pTNM

Ā Ā 

0.11(c)

0-I

6 (5.0)

9 (12.5)

Ā 

II

70 (57.8)

34 (47.2)

Ā 

III - IV

45 (37.2)

29 (40.3)

Ā 

Teaching Hospital

Ā Ā 

0.29(b)

Guadeloupe

44 (37.7)

32 (43.1)

Ā 

Martinique

77 (62.3)

40 (56.9)

Ā 
  1. ADK: adenocarcinoma. Data are given as number and percentage (round brackets) based on the total number of p53 positive and p53 negative cases in GlpeTH and MqueTH. (a)Student t test. (b)Fisherā€™s exact test. (c)Chi-square test. *right, left and transverse.