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Table 1 Prognostic clinicopathological variables as predictors for disease-specific survival of soft tissue sarcomas (univariate analysis, log rank test), N = 193

From: Prognostic impact of Skp2, ER and PGR in male and female patients with soft tissue sarcomas

Characteristic

Patients (n)

Patients (%)

Median survival (months)

5-Year survival (%)

P

Age

     

<20 years

17

9

190

47

0.064

20–59 years

85

44

235

63

 

≥60 years

91

47

111

51

 

Gender

     

Male

81

42

235

60

0.087

Female

112

58

180

53

 

Nationality

     

Norwegian

131

68

228

62

0.005

Russian

62

32

81

44

 

Histology

     

Pleomorphic sarcoma

57

30

52

45

0.031

Leiomyosarcoma

47

24

89

64

 

Liposarcoma

32

17

NR

71

 

MF/MFT

16

8

123

56

 

Angiosarcoma

8

4

10

38

 

Rhabdomyosarcoma

9

5

NR

67

 

MPNST

9

5

NR

56

 

Synovial sarcoma

12

6

31

30

 

Other STS

3

2

NR

-

 

Tumor localization

     

Extremities

78

40

201

56

0.922

Trunk

37

19

214

53

 

Retroperitoneum

27

14

135

51

 

Head/Neck

13

7

191

58

 

Visceral

38

20

202

62

 

Tumor size

     

<5 cm

57

30

257

69

0.026

5–9 cm

73

38

183

54

 

≥10 cm

61

32

127

48

 

Missing

2

1

   

Malignancy grade FNCLCC

     

1

54

28

NR

81

<0.001

2

76

39

80

55

 

3

63

33

28

36

 

Surgical margins

     

Wide

97

50

254

66

<0.001

Non-wide

96

50

128

46

 

Chemotherapy

     

No

156

81

207

57

0.669

Yes

37

19

180

51

 

Radiotherapy

     

No

132

68

216

58

0.190

Yes

61

32

152

52

 
  1. Abbreviations: MF/MFT, malignant fibroblastic/myofibroblastic tumors; MPNST, malignant peripheral nerve sheath tumor; STS, soft tissue sarcomas; NR, not reached; NOS, non specified.