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Table 2 Diagnostic performance of different tests for diagnosis of suspicious metastatic cervical lymph nodes (CLN) from thyroid cancer patients (n = 35)

From: Cervical lymph node metastases from thyroid cancer: does thyroglobulin and calcitonin measurement in fine needle aspirates improve the diagnostic value of cytology?

Test

Sensitivity

Specificity

PPV

NPV

Accuracy

FNAB-C

84.4 (27/32) [67.2-94.7]

N.D. (0/0) [N.D.]

100 (27/27) [87.2-100]

N.D. (0/5) [0-52.2]

84.4 (27/32) [67.2-94.7]

FNAB-Tgp

92.3 (24/26) [74.9-99.1]

83.3 (5/6) [35.9-99.6]

96.0 (24/25) [79.7-99.9]

71.4 (5/7) [29.0-96.3]

90.6 (29/32) [77.7-103.5]

FNAB-Tgm

87.5 (21/24) [67.6-97.3]

100 (6/6) [54.1-100]

100 (21/21) [83.9-100]

66.7 (6/9) [29.9-92.5]

90.0 (27/30) [76.3-103.7]

FNAB-CTm

100 (3/3) [29.2-100]

100 (27/27) [87.2-100]

100 (3/3) [29.2-100]

100 (27/27) [87.2-100]

100 (30/30) [100-100]

  1. PPV, positive predictive value; NPV, negative predictive value; C, cytology; Tgp, thyroglobulin protein; Tgm, thyroglobulin mRNA; CTm, calcitonin mRNA. N.D., non-determined. In round brackets the number of cases. In square brackets the 95% confidence interval.