Table 2 Distribution of clinicopathologic factors in relation to MMR status (n = 474)
Factor | Frequency (%) | ||||
|---|---|---|---|---|---|
MMR deficient | MMR proficient | ||||
Patients (n = 462) | Total number | 103 | (22.3) | 359 | (77.7) |
Sex (n = 462) | Male | 26 | (25.2) | 184 | (51.3) |
Female | 77 | (74.8) | 175 | (48.7) | |
Age (n = 462) | Mean | 76 | 74 | ||
Age ≥60 | 102 | (99.0) | 328 | (91.4) | |
Tumors (n = 474) | Total number | 108 | (22.8) | 366 | (77.2) |
pT stage (n = 450) | pT1 | 2 | (1.9) | 6 | (1.7) |
pT2 | 10 | (9.6) | 37 | (10.7) | |
pT3 | 87 | (83.7) | 224 | (64.8) | |
pT4 | 5 | (4.8) | 79 | (22.8) | |
pN stage (n = 461) | pN0 | 76 | (73.1) | 183 | (51.2) |
pN1 | 23 | (22.1) | 107 | (30.0) | |
pN2 | 5 | (4.8) | 67 | (18.8) | |
pM stage (n = 474) | pM1 | 1 | (0.9) | 10 | (2.7) |
Differentiation (n = 474) | Good/moderate | 42 | (38.9) | 334 | (91.3) |
Poor/no | 66 | (61.1) | 32 | (8.7) | |
Location (n = 473) | Proximal | 99 | (91.7) | 173 | (47.4) |
Distal | 9 | (8.3) | 192 | (52.6) | |
Growth pattern (n = 459) | Expanding | 76 | (73.8) | 27 | (7.6) |
Infiltrating | 27 | (26.2) | 329 | (92.4) | |
Dirty necrosis (n = 467) | Present | 20 | (19.4) | 269 | (73.9) |
Absent | 83 | (80.6) | 95 | (26.1) | |
Mucin/signet-ring differentiation (n = 473) | Present (>50%) | 23 | (21.3) | 15 | (4.1) |
Present (10-50%) | 50 | (46.3) | 81 | (22.2) | |
Absent | 35 | (32.4) | 269 | (73.7) | |
TIL (n = 470) | Present | 72 | (66.7) | 61 | (16.9) |
Absent | 36 | (33.3) | 301 | (83.1) | |