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Figure 2 | BMC Clinical Pathology

Figure 2

From: Women with familial risk for breast cancer have an increased frequency of aldehyde dehydrogenase expressing cells in breast ductules

Figure 2

Frequency of ALDH+ cells in ductules of benign breast tissue from pre-menopausal women with a family history of breast cancer. ALDH+ cells were detected significantly more often in tissue from patients in this group than in control patients. A, Representative image of ALDH+ cell populations (arrows) in breast tissue from a woman with a family history of breast cancer but no BRCA1/2 mutation. ALDH+ cells in the periphery of blood vessels, such as in the large Y-shaped structure in the center of this image, were detected in some cases (not analyzed further in this study). B, Image demonstrating ALDH+ cell populations (arrows) in benign breast tissue from a woman with a BRCA1 mutation. C, Image showing ALDH+ cell populations (arrows) in benign breast tissue from a woman with a BRCA2 mutation. Scale bar in A represents 100 μm in all three images.

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BMC Clinical Pathology

ISSN: 1472-6890

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