Figure 1From: Comparison of metabolic ratios of urinary estrogens between benign and malignant thyroid tumors in postmenopausal women Differential metabolic ratios on estrogen metabolism with statistical significance in benign and malignant papillary thyroid tumors. Estrogen activities were compared in postmenopausal women with benign adenomas (n = 9) and stage I (n = 11) and III/IV (n = 7) malignant carcinomas. The significant metabolic ratios with P < 0.05 in a Kruskal-Wallis test were analyzed with the Mann–Whitney U test between 2 groups, including benign versus stage I PTC, benign versus stage III/IV PTC, and stage I versus stage III/IV PTC. (A) 16α-OH-E1/E1, (B) E3/E2, (C) E2/E1, (D) E3/16α-OH-E1 and (E) 2-OH-E2/E3. * P < 0.02; ** P < 0.002; and *** P < 0.0002.Back to article page