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Table 2 In situ expression of PGs in different sex, age and H. pylori status

From: Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease

  Total   NOR   GS   GA  
  IRS scorea   IRS scorea   IRS scorea   IRS scorea  
In situ PGI staining         
Sex   0.265   0.002   0.599   0.964
Female 4.0(2.0,7.0)   5.0(4.0,7.5)   6.0(4.0,9.0)   2.0(1.0,3.3)  
Male 3.0(0.0,7.0)   9.0(7.0,10.5)   6.0(2.5,8.5)   2.0(1.0,3.0)  
Age(years)   0.003   0.681   0.183   0.563
<50 4.0(2.0,9.0)   7.5(5.5,9.3)   7.0(3.0,10.0)   2.0(1.0,4.0)  
≥50 3.0(0.0,6.0)   7.5(5.0,10.8)   5.0(3.0,7.0)   2.0(1.0,3.0)  
H. pylori IgG   0.359   /   0.515   0.659
EIU < 34 3.0(1.0,6.0)   7.5(5.0,10.0)   5.0(3.0,9.3)   2.0(1.0,3.0)  
EIU ≥ 34 2.0(0.0,6.0)   /   6.0(4.0,8.8)   2.0(1.0,3.5)  
In situ PGII staining         
Sex   0.073   0.363   0.245   0.643
Female 3.0(1.0,7.0)   7.0(4.5,11.0)   6.0(4.0,9.0)   3.0(1.0,5.0)  
Male 5.0(2.0,7.0)   9.0(7.5,10.0)   5.0(3.0,9.0)   2.0(1.3,4.0)  
Age(years)   0.003   0.198   0.260   0.173
<50 5.0(2.0,9.0)   7.5(4.0,9.0)   6.5(3.3,9.8)   3.0(2.0,5.8)  
≥50 3.0(0.0,6.3)   9.5(6.0,11.0)   5.0(2.0,8.0)   2.0(1.0,4.0)  
H. pylori IgG   0.942   /   0.344   0.069
EIU < 34 3.0(1.0,6.0)   8.5(5.8,10.3)   6.0(2.0,9.0)   2.0(1.0,3.0)  
EIU ≥ 34 3.0(0.0,6.0)   /   5.5(4.0,9.8)   3.0(2.0,5.5)  
In situ PGI/PGII staining         
Sex   0.453   0.123   1.000   0.650
Female 0.8(0.4,1.3)   0.8(0.5,1.0)   1.0(0.7,1.5)   0.6(0.2,1.2)  
Male 0.8(0.0,1.1)   1.0(0.8,1.2)   1.0(0.7,1.5)   0.8(0.4,1.0)  
Age(years)   0.011   0.530   0.864   0.462
<50 1.0(0.6,1.3)   1.0(0.6,1.6)   1.0(0.7,1.4)   1.0(0.4,1.0)  
≥50 0.7(0.0,1.0)   01.0(0.8,1.0)   1.0(0.7,1.5)   0.7(0.1,1.0)  
H. pylori IgG   0.062   /   0.763   0.599
EIU < 34 0.9(0.3,1.4)   1.0(0.7,1.1)   1.0(0.7,1.5)   0.8(0.2,2.5)  
EIU ≥ 34 0.6(0.0,1.0)   /   1.0(0.7,1.4)   0.7(0.4,1.0)  
  1. a, IRS of PGI, PGII and PGI/II ratio were represented as median (25%, 75%); b, in situ expression of PGI, PGII, PGI/II ratio between two groups were compared by Mann–Whitney test. Analyses results with P < 0.05 were highlighted in bold characters.