Table 5 Prognostic factors in univariate and multivariate Cox proportional-hazards regression models for disease-specific survival in patients with stage II and III disease
Univariate (Log-rank) | Multivariate | |||||
|---|---|---|---|---|---|---|
n | 5-yr DSS(%) | p | HR | 95%CI | p | |
Age | ||||||
<70 | 65 | 54 | ||||
≥70 | 33 | 64 | 0.63 | |||
Gender | ||||||
female | 22 | 64 | ||||
male | 76 | 56 | 0.49 | |||
Main location | ||||||
middle or lower | 78 | 61 | ||||
upper | 20 | 44 | 0.24 | |||
WHO pathological type | ||||||
differentiated | 39 | 69 | 1 | |||
undifferentiated | 59 | 50 | 0.077 | 1.7 | 0.86-3.3 | 0.13 |
Depth of invasion | ||||||
T1-3 | 48 | 85 | 1 | |||
T4 | 50 | 32 | <0.001 | 5.5 | 2.5-12 | <0.001 |
Lymph node metastasis | ||||||
negative | 20 | 89 | 1 | |||
positive | 78 | 49 | 0.004 | 3.0 | 0.92-9.9 | 0.070 |
EphA2 | ||||||
low | 18 | 83 | 1 | |||
high | 80 | 52 | 0.019 | 1.7 | 0.52-5.7 | 0.38 |
EphA4 | ||||||
low | 28 | 79 | 1 | |||
high | 70 | 49 | 0.007 | 2.6 | 1.1-6.3 | 0.039 |
ephrinA1 | ||||||
low | 40 | 51 | ||||
high | 58 | 62 | 0.39 | |||