Table 2 Literature review of clinicopathological data of primary thymic adenocarcinomas
Author | Year | Sex | Age | Symptoms | Tumor type | Site | RX | Outcome | Associated findings |
|---|---|---|---|---|---|---|---|---|---|
Moriyama S [2] | 1989 | F | 51 | Hyperthyroidism | Papillo-tubular | Right lobe of the thymus | S | No recurrence for 14 years | Multiple thymic cysts |
Babu MK [19] | 1994 | M | 50 | NA | Conventional | NA |  | Alive after 4 months | Congenital thymic cyst |
Makino Y [6] | 1998 | M | 39 | Chest pain | Papillary carcinoma | NA | S,R | Alive after 5 months | NA |
Matsuno [5] | 1998 | M | 70 | Not mentioned | Papillary carcinoma | Anterior mediastinum | S,R | Recurrence after 8 months | Numerous psammoma bodies |
F | 69 | Not mentioned | Papillary carcinoma | Left lower pole of the thymus | S | Not mentioned | Thymoma of medullary type | ||
F | 61 | Not mentioned | Papillary carcinoma | Substernalmediastinal mass | S,R,C | Died after 7 months | Chronic elephantiasis nostrasverrucosum in skin | ||
M | 57 | Not mentioned | Papillary carcinoma | Anterior mediastinum | S,R,C | Alive after 5 years | No | ||
Shimono [20] | 2001 | M | 61 | facial edema, general fatigue | Not specified | Anterior mediastinum | S,R,C | Alive after 53 months | No |
Zaitlin [21] | 2003 | F | 51 | Asymptomatic | Papillary carcinoma | Anterior left mediastinum | S,R | Died after 26 months | Thymic cyst |
Choi WW [7] | 2003 | M | 39 | Cough&lethargy | Papillary carcinoma | Anterior mediastinum | S,R,C | Alive after 3 years | NA |
M | 15 | Dry cough | Mucinous carcinoma | Right anterior mediastinum | S,R | Died after 26 months | Thymiccyst&cribriform, carcinomatous gland in thymic medulla | ||
Misao [10] | 2004 | M | 59 | Accidental finding in chest x ray | Not specified | Anterior Mediastinum | S,C | Died after 24 months | No |
Takahashi F [1] | 2004 | M | 49 | Accidental finding in chest x ray | Mucinous carcinoma | Anterior mediastinum | R | Died 11 months after DX | Increased CA19-9, CEA |
Seki, ErinaMD [11] | 2004 | M |  | Left shoulder pain | Mucinous adenocarcinoma with pleural dissemination | Anterior mediastinum | R.C | Alive in 11 months after surgery. | No |
Yoshino M [12] | 2005 | F | 29 | Accidental finding in chest x ray | Papillary carcinoma | Anterior mediastinum | S | Not mentioned | Type A thymoma, Psammoma bodies and follicles |
PayalKapur [4] | 2006 | M | 41 | Not mentioned | Mucinous carcinoma | Anterior mediastinum | R,c | 2 recurrence in 3 years | Multiple thymic cysts |
ToyomitsuSawai [9] | 2006 | M | 34 | Accidental finding in chest x ray | Moderately differentiated adenocarcinoma | Right anterior mediastinum | R,C | Lung metastasis after eight months of surgery | Increased CA19-9, CEA |
Seong H. Ra [13] | 2007 | F | 61 | Hoarseness, dysphagia, left shoulder pain, and fatigue | Mucinous carcinoma | Superoanterior mediastinum | S,R | Metastatic disease to retroperitoneal lymph nodes at 5 months | Psammoma bodies |
F | 82 | Shortness of breath, chest tightness, back stiffness, and weight loss of 15 lb | Mucinous carcinoma | Anterior mediastinum | S | Passed away due to surgical complications | Thymiccyst, signetringlike features | ||
Furtado [14] | 2008 | M | 44 | Accidental finding in chest x ray | Papillary carcinoma | Pretracheal region | S,R,C | Alive for 24 months | Psammoma bodies |
HosakaY [15] | 2009 | M | 36 | Accidental finding in chest x ray | Moderately differentiated adenocarcinoma with papillary formation | Right anterior mediastinum | R | Alive in 11 years after surgery | Type AB thymoma |
Toshiji I [16] | 2009 | M | 54 | Cough, fever, dyspnea,chest pain, facial edema | Poorly differentiated sarcomatoid tumor cells partially composed of papillotubular adenocarcinoma | Anterior mediastinum | R | Passed away 56 days after the initialsymptoms | Slight elevation of sialyl Lewis-x antigen,soluble interleukin-2 receptor |
Maeda D [17] | 2009 | F | 52 | Bulging of the left parasternal region | Mucinous carcinoma | Anterior mediastinum | S,R,C | Lung metastasis after 7 months | Thymic cyst |
M | 38 | Chest pain | Mucinous carcinoma | Anterior mediastinum | S,R,C | Died 12 months after diagnosis | No | ||
M | 55 | Chest tightness | Mucinous carcinoma | Anterior mediastinum | S,R,C | Died 24 months after diagnosis | No | ||
Yong Joon Ra [18] | 2010 | M | 68 | Dyspnea and chest pain on left anteriorchest | Conventional | Anterior mediastinam | Not mentioned | Not mentioned | Slightly increased (β-hCG) level |
Current case | 2010 | F | 28 | Neck and right upper extremity pain and dyspnea | Mucinous | Anterior mediastinam | S,R,C | Two recurrences in two years follow up | Thymic cyst and psammoma bodies, increased CA19-9 |