Table 4 Expression levels of serum miRNAs (mean ± SD), PG (median ± SD) between different gastric disease groups when stratified by H.pylori status
Variables | CON | AG | GC | P- value | |
|---|---|---|---|---|---|
Hp- | |||||
miR-20a-5p | 3.83 ± 0.71 | 3.88 ± 0.59 | 3.85 ± 0.70 | 0.926 | |
Male | 3.84 ± 0.72 | 3.90 ± 0.59 | 3.89 ± 0.34 | 0.931 | |
Female | 3.82 ± 0.71 | 3.86 ± 0.60 | 3.75 ± 0.53 | 0.881 | |
let-7a | 3.74 ± 0.31 | 3.81 ± 0.31 | 3.76 ± 0.25 | 0.505 | |
Male | 3.73 ± 0.31 | 3.84 ± 0.34 | 3.77 ± 0.25 | 0.36 | |
Female | 3.76 ± 0.30 | 3.76 ± 0.28 | 3.74 ± 0.27 | 0.972 | |
miR-320a | 5.02 ± 0.48 | 4.90 ± 0.45 | 4.91 ± 0.47 | 0.311 | |
Male | 5.03 ± 0.50 | 4.97 ± 0.48 | 4.98 ± 0.44 | 0.813 | |
Female | 4.99 ± 0.44 | 4.81 ± 0.41 | 4.74 ± 0.50 | 0.216 | |
PGA | 134.99 ± 92.27 | 96.78 ± 76.05 | 141.99 ± 125.80 | 0.056 | |
PGC | 15.13 ± 13.67 | 10.37 ± 9.02 | 23.15 ± 25.11 | 0.001 | |
PGA/PGC | 10.66 ± 4.81 | 11.00 ± 6.04 | 9.17 ± 6.28 | 0.22 | |
Hp+ | |||||
miR-20a-5p | 3.69 ± 0.78 | 3.79 ± 0.79 | 3.81 ± 0.66 | 0.743 | |
Male | 3.75 ± 0.86 | 3.90 ± 0.31 | 3.86 ± 0.82 | 0.785 | |
Female | 3.62 ± 0.66 | 3.53 ± 0.55 | 3.74 ± 0.43 | 0.542 | |
let-7a | 3.68 ± 0.38 | 3.74 ± 0.27 | 3.74 ± 0.31 | 0.661 | |
Male | 3.70 ± 0.31 | 3.73 ± 0.30 | 3.77 ± 0.33 | 0.717 | |
Female | 3.66 ± 0.48 | 3.75 ± 0.18 | 3.70 ± 0.28 | 0.795 | |
miR-320a | 4.95 ± 0.44 | 4.98 ± 0.45 | 4.89 ± 0.40 | 0.634 | |
Male | 5.01 ± 0.49 | 5.05 ± 4.59 | 5.05 ± 0.46 | 0.961 | |
Female | 4.87 ± 0.36 | 4.81 ± 0.38 | 4.72 ± 0.36 | 0.471 | |
PGA | 162.15 ± 112.44 | 125.81 ± 92.66 | 114.74 ± 75.23 | 0.058 | |
PGC | 24.82 ± 20.80 | 17.86 ± 13.95 | 23.10 ± 20.16 | 0.182 | |
PGA/PGC | 7.91 ± 4.49 | 7.97 ± 3.70 | 6.16 ± 3.57 | 0.06 | |