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Table 2 Diagnostic performance of the tests for high-risk lesions

From: Evaluation of chemiluminescence, toluidine blue and histopathology for detection of high risk oral precancerous lesions: A cross-sectional study

Protocol Parameter Compared to HPMV Using LCA
CHEM Sensitivity 1.00 (0.82-1.00) 1.00 (0.99-1.00)
  Specificity 0.01 (0.00-0.06) 0.01 (0.00-0.04)
TBLU Sensitivity 0.59 (0.36-0.78) 0.99 (0.92-1.00)
  Specificity 0.79 (0.69-0.87) 1.00 (0.99-1.00)
CHTB Sensitivity 0.59 (0.36-0.78) 1.00 (0.99-1.00)
  Specificity 0.78 (0.68-0.86) 1.00 (0.99-1.00)
HPMV Sensitivity --- 0.37 (0.19-0.55)
  Specificity --- 0.90 (0.83-0.97)
Prevalence of HRL 0.17 (0.10-0.24) 0.27 (0.18-0.36)
  1. CHEM, chemiluminescence; TBLU, toluidine blue retention; CHTB, toluidine blue retention and chemiluminescence; HPMV, histopathology majority vote; LCA, latent class analysis; HRL, high risk lesion