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Table 1 Relationship between Bax expression, Bcl-2 expression the expression of VEGF, Cytochrome-c, Caspase-3, or MMP-9 and T stage or N stage

From: Low Mmp 9 and VEGF levels predict good oncologic outcome in mid and low rectal cancer patients with neoadjuvant chemoradiation

 

Patients (n)

VEGF

Cy-c

Casp-3

MMP-9

Bax expression

Bcl-2 expression

      

<10%--->10%

<10%--->10%

T0

7

129.7 ± 67.7

68.3 ± 54.6

0.22 ± 0.1

488.6 ± 405.1

1(14)----6(86)

4(29)-----3(20)

T2-T3

22

516.51 ± 69.63

54.48 ± 28.85

0.07 ± 0.043

1166.6 ± 745.9

18(82)--4(18)

10(71)---12(80)

P value

 

0.051

0.72

0.19

0.04

0.001

0.59

      

<10%--->10%

<10%--->10%

No

19

381.4 ± 631.1

61.2 ± 38.6

0.12 ± 0.2

991.4 ± 803.6

11(58)---8(42)

10(71)---9(60)

N(+)

10

528.67 ± 531.40

50.28 ± 28.15

0.06 ± 0.47

1064.97 ± 620.8

8(80)-----2(20)

4(29)-----6(40)

P value

 

0.20

0.68

0.21

0.50

0.23

0.52

  1. Units: VEGF, pg/ml; Cy-c: Cytochrome-c, ng/ml; Casp-3: Caspase-3, pmol AMC/min/mg; MMP-9, ng/ml.
  2. *Numbers in parentheses indicate percentages.