Cytokine | PHA | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Controls | Patients | Cmean/ Pmean | P-value | |||||||||||
N | Mean | SD | Min. | Max. | Med. | N | Mean | SD | Min. | Max. | Med. | |||
MCP-1 | 90 | 3497 | 4384 | 69 | >OOR | 1823 | 109 | 1968 | 1993 | 86 | >OOR | 1310 | 1.8 | 0.003 |
IL-5 | 32 | 47.7 | 150.1 | <OOR | 853 | 14.1 | 48 | 7 | 17 | <OOR | 89 | 1.5 | 7 | 0.136 |
IL-6 | 91 | 2799 | 4182 | 1.2 | 15592 | 273 | 110 | 276 | 437 | 3.1 | 2255 | 108 | 10.2 | <.001 |
IL-8 | 89 | 17456 | 24246 | 161 | >OOR | 4933 | 110 | 5751 | 6123 | 135 | 37981 | 3144 | 3 | <.001 |
IL-10 | 65 | 80 | 94 | <OOR | 352 | 38 | 103 | 12 | 15 | <OOR | 84 | 6.8 | 6.5 | <.001 |
IFNγ | 70 | 1516 | 2425 | <OOR | 16902 | 670 | 101 | 569 | 1920 | <OOR | 15318 | 124 | 2.7 | 0.007 |
MIP-1α | 91 | 1084 | 1773 | 1.9 | 9159 | 240 | 110 | 204 | 272 | 5.7 | 1598 | 109 | 5.3 | <.001 |
MIP-1β | 83 | 4413 | 5228 | 122 | >OOR | 2282 | 109 | 2900 | 2417 | 395 | >OOR | 2259 | 1.5 | 0.016 |
Cytokine | PMA/Ionomycin | |||||||||||||
Controls | Patients | C mean / P mean | P- value | |||||||||||
N | Mean | SD | Min. | Max. | Med. | N | Mean | SD | Min. | Max. | Med. | |||
MCP-1 | 91 | 1224 | 1126 | 150 | 8295 | 874 | 108 | 436 | 421 | <OOR | 2363 | 292 | 2.8 | <.001 |
IL-5 | 87 | 63.8 | 63.9 | <OOR | 374.5 | 42.5 | 98 | 36 | 54 | <OOR | 441 | 17 | 1.8 | 0.002 |
IL-6 | 91 | 532 | 474 | 26 | 2108 | 350 | 108 | 242 | 301 | <OOR | 1509 | 109 | 2.2 | <.001 |
IL-8 | 90 | 17607 | 10103 | 5724 | >OOR | 13677 | 109 | 8756 | 6416 | 215 | >OOR | 7503 | 2 | <.001 |
IL-10 | 87 | 63 | 60 | <OOR | 254 | 40 | 90 | 27 | 37 | <OOR | 230 | 11 | 2.4 | <.001 |
IFNγ | 91 | 36726 | 55772 | 205 | 339591 | 16130 | 103 | 14584 | 23047 | <OOR | 144516 | 5636 | 2.5 | 0.001 |
MIP-1α | 90 | 1246 | 1051 | 105 | >OOR | 987 | 109 | 308 | 294 | <OOR | 1551 | 191 | 4 | <.001 |
MIP-1β | 80 | 6389 | 4915 | 254 | >OOR | 5177 | 106 | 3086 | 4040 | 9.5 | >OOR | 1517 | 2.1 | <.001 |