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Table 3 Concentrations of cytokines in stimulated PBMC cultures of controls

From: Unique immunologic patterns in fibromyalgia

Cytokine

Median detection ranges

Unstimulated

PHA-stimulated

PMA/Ionomycin-stimulated

N

Mean

SD

N

Mean

SD

P-value

N

Mean

SD

P-value

MCP-1

3-14,000

50

299

217

90

3497

4384

<.001

91

1224

1126

<.001

IL-5

1-13,000

16

2.6

1.3

32

48

150

0.10

87

64

64

<.001

IL-6

1-33,000

59

215

380

91

2799

4182

<.001

91

532

474

<.001

IL-8

2-60,000

56

771

659

89

17456

24246

<.001

90

17607

10103

<.001

IL-10

2-63,000

44

23

29

65

80

94

<.001

87

63

60

<.001

IFN-γ

5-224,000

40

538

338

70

1516

2425

0.001

91

36726

55772

<.001

MIP-1α

1-7,000

56

33

73

91

1084

1773

<.001

90

1246

1051

<.001

MIP-1β

5-14,000

57

222

174

83

4413

5228

<.001

80

6389

4915

<.001

  1. Concentrations of cytokines in pg/ml are shown.
  2. N, number of subjects whose cytokine values were within the detection ranges.