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Table 3 Concentrations of cytokines in stimulated PBMC cultures of controls

From: Unique immunologic patterns in fibromyalgia

Cytokine Median detection ranges Unstimulated PHA-stimulated PMA/Ionomycin-stimulated
N Mean SD N Mean SD P-value N Mean SD P-value
MCP-1 3-14,000 50 299 217 90 3497 4384 <.001 91 1224 1126 <.001
IL-5 1-13,000 16 2.6 1.3 32 48 150 0.10 87 64 64 <.001
IL-6 1-33,000 59 215 380 91 2799 4182 <.001 91 532 474 <.001
IL-8 2-60,000 56 771 659 89 17456 24246 <.001 90 17607 10103 <.001
IL-10 2-63,000 44 23 29 65 80 94 <.001 87 63 60 <.001
IFN-γ 5-224,000 40 538 338 70 1516 2425 0.001 91 36726 55772 <.001
MIP-1α 1-7,000 56 33 73 91 1084 1773 <.001 90 1246 1051 <.001
MIP-1β 5-14,000 57 222 174 83 4413 5228 <.001 80 6389 4915 <.001
  1. Concentrations of cytokines in pg/ml are shown.
  2. N, number of subjects whose cytokine values were within the detection ranges.
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