Cytokine | Median detection ranges | Unstimulated | PHA-stimulated | PMA/Ionomycin-stimulated | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
N | Mean | SD | N | Mean | SD | P-value | N | Mean | SD | P-value | ||
MCP-1 | 3-14,000 | 50 | 299 | 217 | 90 | 3497 | 4384 | <.001 | 91 | 1224 | 1126 | <.001 |
IL-5 | 1-13,000 | 16 | 2.6 | 1.3 | 32 | 48 | 150 | 0.10 | 87 | 64 | 64 | <.001 |
IL-6 | 1-33,000 | 59 | 215 | 380 | 91 | 2799 | 4182 | <.001 | 91 | 532 | 474 | <.001 |
IL-8 | 2-60,000 | 56 | 771 | 659 | 89 | 17456 | 24246 | <.001 | 90 | 17607 | 10103 | <.001 |
IL-10 | 2-63,000 | 44 | 23 | 29 | 65 | 80 | 94 | <.001 | 87 | 63 | 60 | <.001 |
IFN-γ | 5-224,000 | 40 | 538 | 338 | 70 | 1516 | 2425 | 0.001 | 91 | 36726 | 55772 | <.001 |
MIP-1α | 1-7,000 | 56 | 33 | 73 | 91 | 1084 | 1773 | <.001 | 90 | 1246 | 1051 | <.001 |
MIP-1β | 5-14,000 | 57 | 222 | 174 | 83 | 4413 | 5228 | <.001 | 80 | 6389 | 4915 | <.001 |