| |
OS
|
DFS
|
PFS
|
|---|
|
Variables
|
N=97
|
HR
|
95%CI
|
p
|
N=93
|
HR
|
95%CI
|
p
|
N=97
|
HR
|
95%CI
|
p
|
|---|
|
Univariate analysis
|
|
Age
| | | | | | | | | | | | |
|
<65 vs ≥65
|
103
|
1.23
|
0.46-3.28
|
0.68
|
93
|
1.06
|
0.41-2.75
|
0.90
|
102
|
1.37
|
0.49-3.79
|
0.54
|
|
FIGO stage
| | | | | | | | | | | | |
|
III-IV vs I-II
|
97
|
17.05
|
5.47-53.17
|
<0.01
|
93
|
5.88
|
2.25-15.34
|
<0.01
|
96
|
16.73
|
5.28-53.03
|
<0.01
|
|
Tumor grade
| | | | | | | | | | | | |
|
G1 vs G2-G3
|
103
|
0.001
|
-*
|
0.68
|
99
|
0.155
|
0.02-1.18
|
0.07
|
102
|
0.001
|
-*
|
0.69
|
|
Lymph node involvement
| | | | | | | | | | | | |
|
positive vs negative
|
87
|
10.17
|
3.22-32.11
|
<0.01
|
85
|
6.05
|
2.09-17.51
|
<0.01
|
86
|
14.07
|
4.08-48.49
|
<0.01
|
|
Trop-2 IHC
| | | | | | | | | | | | |
|
score=3 vs score 0/1/2
|
103
|
2.60
|
0.94-7.19
|
0.06
|
99
|
3.36
|
1.26-8.92
|
0.01
|
102
|
2.80
|
0.99-7.87
|
0.05
|
|
Multivariate analysis
|
|
Trop-2 IHC
|
97
| | | |
93
| | | |
97
| | | |
|
score=3 vs score 0/1/2
| |
1.83
|
0.65-5.18
|
0.25
| |
2.82
|
1.05-7.58
|
0.04
| |
1.76
|
0.63-4.88
|
0.28
|
|
FIGO stage
|
97
| | | |
93
| | | |
97
| | | |
|
III-IV vs I-II
| |
15.94
|
5.08-50.04
|
<0.001
| |
5.36
|
2.04-14.08
|
<0.001
| |
16.73
|
5.31-52.73
|
<0.001
|
- *Because of the small number of events (deaths and progressions) in the G1 EEC category, the confidence interval was not reliable.
