TY - JOUR AU - Bignotti, Eliana AU - Zanotti, Laura AU - Calza, Stefano AU - Falchetti, Marcella AU - Lonardi, Silvia AU - Ravaggi, Antonella AU - Romani, Chiara AU - Todeschini, Paola AU - Bandiera, Elisabetta AU - Tassi, Renata A. AU - Facchetti, Fabio AU - Sartori, Enrico AU - Pecorelli, Sergio AU - Roque, Dana M. AU - Santin, Alessandro D. PY - 2012 DA - 2012/11/14 TI - Trop-2 protein overexpression is an independent marker for predicting disease recurrence in endometrioid endometrial carcinoma JO - BMC Clinical Pathology SP - 22 VL - 12 IS - 1 AB - Endometrial cancer is the most common gynecologic malignancy in developed countries. Trop-2 is a glycoprotein involved in cellular signal transduction and is differentially overexpressed relative to normal tissue in a variety of human adenocarcinomas, including endometrioid endometrial carcinomas (EEC). Trop-2 overexpression has been proposed as a marker for biologically aggressive tumor phenotypes. SN - 1472-6890 UR - https://doi.org/10.1186/1472-6890-12-22 DO - 10.1186/1472-6890-12-22 ID - Bignotti2012 ER -