Figure 4

Immunohistochemical analysis of lung tumor samples. Ninety-five lung tumor sections were stained for their expression of TNC and TNW and classified as described in Figure 2. The number of tumors classified in each category for TNC and TNW is shown as pie charts (A). A double-entry table details how many tumors show each combination of TNW/TNC expression (B). Twenty-one pairs of matching lung normal/tumor lung tissue samples were stained for their expression of TNW and TNC. Representative stainings are shown: From top to bottom, tumor pictures represent increasing scores of TNW from low, moderate to high with the corresponding tissues stained for TNC in the right panels. From top to bottom an adenocarcinoma, a squamous carcinoma and an undifferentiated carcinoma are shown (C). Every picture is acquired at the same magnification (Scale bar = 200 μm).