Table 2 Methylation status of MMP-2 and MMP-9 genes in ameloblastoma and healthy gingiva
From: Epigenetic regulation of matrix metalloproteinase expression in ameloblastoma
Parameters | Ameloblastoma (n = 12) | Healthy gingiva (n = 12) | p-value* |
|---|---|---|---|
MMP-2 methylation | |||
Methylated | 05 (41.7%) | 12 (100.0%) | 0.002* |
Unmethylated | 07 (58.3%) | 0 (0.0%) | |
MMP-9 methylation/restriction site digested by HhaI | |||
Methylated | 0 (0.0%) | 06 (50.0%) | 0.006* |
Unmethylated | 12 (100.0%) | 06 (50.0%) | |
MMP-9 methylation/restriction site digested by AciI | |||
Methylated | 01 (8.3%) | 0 (0.0%) | 0.317 |
Unmethylated | 11 (91.7%) | 12 (100.0%) | |