Table 1

Amino acid

Alanine, aspartate metabolism

alanine

1.6

0.013

0.049

aspartate

2.2

0.013

0.049

N-acetylaspartate

6.1

0.020

0.049

Butanoate metabolism

2-aminobutyrate

1.8

0.014

0.049

Cysteine, methionine metabolism

cysteine

4.6

0.049

0.061

cystine

2.9

0.024

0.049

methionine

3.6

0.012

0.049

S-adenosylhomocysteine

1.6

0.004

0.049

Glutamate metabolism

glutamate

2.4

0.019

0.049

N-acetyl-aspartyl-glutamate

1.9

0.014

0.049

Glutathione metabolism

5-oxoproline

1.9

0.017

0.049

cysteine-glutathione disulfide

3.4

0.043

0.060

Glycine, serine, threonine metabolism

betaine

2.3

0.022

0.049

glycine

2.6

0.020

0.049

serine

2.1

0.009

0.049

threonine

1.4

0.003

0.049

Histidine metabolism

histidine

1.5

0.001

0.043

Lysine metabolism

2-aminoadipate

2.1

0.021

0.049

lysine

2.3

0.027

0.052

Phenylalanine, tyrosine metabolism

phenylalanine

1.8

0.011

0.049

tyrosine

1.9

0.014

0.049

Tryptophan metabolism

tryptophan

1.9

0.010

0.049

Urea cycle; arginine, proline metabolism

arginine

1.2

0.033

0.056

ornithine

2.7

0.019

0.049

proline

1.6

0.007

0.049

trans-4-hydroxyproline

2.1

0.036

0.056

Valine, leucine, isoleucine metabolism

isoleucine

1.8

0.016

0.049

leucine

1.8

0.010

0.049

valine

1.6

0.016

0.049

Carbohydrate

Aminosugars

N-acetylglucosamine

5.9

0.028

0.052

Glycolysis

glucose 1-phosphate

0.7

0.033

0.056

Pentose metabolism

ribose

2.7

0.018

0.049

Cofactors and vitamins

Pantothenate

pantothenate

2.3

0.008

0.049

Tocopherol

alpha-tocopherol

2.2

0.041

0.058

Energy

Krebs cycle

fumarate

2.1

0.007

0.049

malate

2.0

0.006

0.049

succinate

1.6

0.009

0.049

succinylcarnitine

2.2

0.041

0.058

Lipid

Carnitine metabolism

3-dehydrocarnitine

1.9

0.023

0.049

acetylcarnitine

1.6

0.015

0.049

carnitine

1.7

0.033

0.056

deoxycarnitine

1.6

0.010

0.049

Essential fatty acid

docosahexaenoate

3.2

0.046

0.060

docosapentaenoate

4.2

0.018

0.049

Fatty acid metabolism

butyrylcarnitine

1.9

0.012

0.049

propionylcarnitine

2.0

0.036

0.056

4-hydroxybutyrate

2.1

0.023

0.049

Glycerolipid metabolism

choline

1.7

0.004

0.049

ethanolamine

3.4

0.039

0.056

glycerol

1.9

0.047

0.060

glycerophosphorylcholine

1.8

0.022

0.049

Long chain fatty acid

10-nonadecenoate

2.8

0.036

0.056

dihomo-linoleate

4.8

0.038

0.056

eicosenoate

3.0

0.013

0.049

myristoleate

1.7

0.045

0.060

oleate

2.1

0.038

0.056

Lysolipid

1-arachidonoylglycerophosphoethanolamine

1.9

0.007

0.049

1-arachidonoylglycerophosphoinositol

2.2

0.006

0.049

1-linoleoylglycerophosphoethanolamine

2.6

0.020

0.049

1-oleoylglycerophosphoethanolamine

2.4

0.007

0.049

1-oleoylglycerophosphoinositol

3.7

0.035

0.056

1-oleoylglycerophosphoserine

2.6

0.022

0.049

1-palmitoylglycerophosphoinositol

3.3

0.047

0.060

1-stearoylglycerophosphoethanolamine

2.2

0.019

0.049

1-stearoylglycerophosphoinositol

4.0

0.044

0.060

2-oleoylglycerophosphoethanolamine

2.4

0.004

0.049

2-palmitoylglycerophosphoethanolamine

2.1

0.027

0.052

Medium chain fatty acid

caprylate

1.2

0.046

0.060

Nucleotide

Purine and pyrimidine

methylphosphate

2.2

0.018

0.049

Purine metabolism, hypoxanthine/inosine

hypoxanthine

2.2

0.004

0.049

inosine

1.6

0.026

0.052

xanthine

5.2

0.030

0.055

xanthosine

2.0

0.014

0.055

Purine metabolism

adenine

1.8

0.038

0.056

guanosine

1.6

0.035

0.056

Pyrimidine metabolism

cytidine

1.9

0.034

0.056

pseudouridine

1.3

0.024

0.049

uracil

4.0

0.003

0.049

uridine

1.9

0.008

0.049

Peptide

gammaglutamyl

gamma-glutamylglutamate

2.3

0.032

0.056

gamma-glutamylglutamine

3.3

0.033

0.056

Other

Benzoate metabolism

benzoate

1.4

0.045

0.060

Other

glycerol 2-phosphate

2.1

0.028

0.052