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Figure 1 | BMC Clinical Pathology

Figure 1

From: Methyl-binding domain protein-based DNA isolation from human blood serum combines DNA analyses and serum-autoantibody testing

Figure 1

Extraction of cell free DNA from control individuals. Box plot of DNA amount isolated from 1 ml serum or plasma from (1) Austrian Institute of Technology (n = 12), (2) Austrian Red Cross (n = 24) and (3) AKH (n = 24). Serum DNA levels were dependent on serum source. Using the silica-based extraction protocol, mean amounts of DNA could be isolated ranging from (1), 11.9 ± 10.9 ng/ml (mean ± SD) and (3), 12.2 ± 9.7 ng/ml to (2), 39.7 ± 32.8 ng/ml. By contrast using the MBD-based protocol, serum DNA concentrations of (1) 2.5 ± 1.9 ng/ml, (2) 11.5 ± 7.3 ng/ml and (3) 2.4 ± 1 ng/ml were observed.

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BMC Clinical Pathology

ISSN: 1472-6890

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