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Figure 4 | BMC Clinical Pathology

Figure 4

From: SNAI1 expression and the mesenchymal phenotype: an immunohistochemical study performed on 46 cases of oral squamous cell carcinoma

Figure 4

Immunohistochemical profile of OSCC with sarcomatoid component, Case 1. A, SNAI1; B, E-cadherin; C, FAK and D, p63 are differentially expressed in sarcomatoid (A+C) and squamous (B+D) component. Magnified inserts correspond to framed areas in the section overview. An asterisk in insert C indicates strands of squamous cell carcinoma intermingled with the sarcomatoid component. Dual staining of SNAI1 (nuclear, brown) and E, HMWK or F, Vimentin (red) illustrates the mesenchymal character of the sarcomatoid tumor component. G, Lymph node metastasis with focal E-cadherin loss (arrow).

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BMC Clinical Pathology

ISSN: 1472-6890

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